Question
QUESTION: Respected Sirs
I am 66 years. I have some(little)knee pain(NOT MUCH),BUT HAVE GOT GOOD
PAIN IN TIBIA(Front bone in between knee and foot)and heavy calf muscle pain which aggravates
during walking.Leg veins are NOT PROMINENT,NO SWELLING ANYWHERE.
My body structure is lean,Weight-62 Kg,Height-5 Ft 8 inches

A)Although there is no pain sometime while bending the knees some crunching/creaking sound
comes.Whether the problem radiates to lower limbs from Knee
X Ray of knees (both legs(AP plus Lateral)shows EARLY OA CHANGES, BOTH KNEE JOINT SPACES
ARE SLIGHTLY DIMINISHED(not uncommon for a 66 year old man).Lateral Picture is ok
B)As the pain is in the lower portion(TIBIA and SHIN) to check whether there is less blood
flow in lower limbs(Peripheral Artery Disease. Doppler Ultrasonography of lower limbs was
done and the result shows
B)No evidence of Deep Vein Thrombosis,b)No soft tissue abnormality,BUT Diffuse
Artherosclerotic wall thickening of lower limb arteries,bur flow and velocity is NORMAL
C)TO CHECK WHETHER whether there is Muscle Dystrophy Creatine Phosphokinase Level in Blood was
measured and found to be high 253 instead of normal BELOW 171
D)As I am very fond of walking whether it be should be done,but for Knee Arthritis walking is
restricted.However as per advice I do Knee Exercise without STRAINING MUCH
E)I have no Sugar/Calcium /Potassium/Uric Acid/Creatinine /Urea level is normal
F)I only take BP medicines Attenol-25, Losartan-25 and Asprin-75 once daily each tablet and
Cholesterol lowering/controlling drugs(Statin )
G) THIS MUSCLE DESTROPHY IS NOT PROBABLY CURABLE,WHETHER MUSCLE RELAXTANTS WILL GIVE SOME
RELIEF.WHAT MEDICINES CAN BE TAKEN.I have taken Carnisure(CARNITINE SUPPLEMENT) without much
improvement.
With thanks

ANSWER: Dear to ,

This is just to let you know that I'm back from my trip and am working on my response to you. I'll follow up with detailed answer, which can take a couple of days. Thank you for your patience

Tanya Zilberter

---------- FOLLOW-UP ----------

QUESTION: I have not yet received the reply. Please help regarding Muscle Dystrophy

Answer
Dear Kalyan,

Muscle wasting conditions should be take care in order to preserve the proper metabolic level, which otherwise follow a vicious circle: decreased muscle mass result in decrease activity resulting in more muscle muss loss in further protein depletion... and the circle goes on.

Currently, the therapies development targets the protein depletion prevention in order to interrupt the vicious circle. The attention is being paid to Myostatin blockers used in cancer therapy as well as in kidney diseases and some cases of hear failure - exactly to fight protein wasting occurring in all these diseases. Ask your health care provider about antimyostatin antibody therapy.

Other than that, you might want to make it sure you have enough of good quality protein in your diet and stimulate your muscle by bearable exercises, dry brush massage, acupuncture, etc. Please take a look at the site explaining the significance of mechanical tactile stimulation as a yet one more idea.


I wish I could be of more help but hope I gave you some information. Ask me any further questions!

Tanya Zilberter