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Soft Tissue Knee Injury: Practice Essentials, Background, Pathophysiology
9/26 11:25:15

Practice Essentials

Soft tissue knee injuries are some of the most common and clinically challenging musculoskeletal disorders seen in the emergency department. Accurate and timely diagnosis increases the likelihood of fully restoring normal and pain-free use of the affected knee.

The image below depicts the normal anatomy of the knee.

Anatomy of the knee. Anatomy of the knee.

Signs and symptoms

The history should focus on the following:

  • Confirming that an acute traumatic event occurred
  • Documenting the mechanism of injury (including the circumstances of the injury)
  • Assessing the stability of the joint
  • Determining the type and location of the pain
  • Evaluating the onset and degree of knee effusion
  • Assessing joint mobility (eg true locking vs pseudolocking)

The initial physical examination focuses on inspection, palpation, and neurovascular evaluation. Steps that may be useful include the following:

  • Observation of the patient’s stance and gait, if possible
  • Inspection of the knee
  • Ballottement of the patella
  • Measurement of the Q angle
  • Inspection and palpation of the popliteal fossa
  • First and second Steinmann signs
  • Payr sign
  • Patellar apprehension sign
  • Palpation of the anterior aspects of both thighs (in quadriceps rupture)
  • Palpation of the relevant bursae (in bursal injuries)
  • In children, palpation of the epiphyses
  • Range-of-motion (ROM) testing
  • Lachman maneuver
  • Anterior and posterior drawer tests
  • Tibial sag test
  • Pivot-shift test
  • McMurray test
  • Apley compression test
  • Thessaly and Ege tests

See Clinical Presentation for more detail.

Diagnosis

The following laboratory studies may be helpful:

  • Blood typing and screening
  • Complete blood count (CBC)
  • Erythrocyte sedimentation rate (ESR)
  • Serum electrolytes
  • Blood glucose
  • Blood urea nitrogen (BUN) and creatinine
  • Analysis of aspirated synovial fluid for white blood cell (WBC) count and differential and for glucose and protein levels

Plain radiographs are recommended for the following scenarios:

  • Patients older than 55 years
  • Patients with tenderness over the fibular head
  • Patients with discomfort confined to the patella upon palpation
  • Patients unable to flex the knee to 90°
  • Patients incapable of bearing weight, immediately and in the ED, for at least 4 steps

Other diagnostic procedures that may be helpful are as follows:

  • MRI
  • Ultrasonography
  • Arteriography (when a knee dislocation is strongly suspected)
  • Injection of methylene blue
  • Knee joint aspiration

See Workup for more detail.

Management

General treatment principles include the following:

  • Aside from the particular injury, treatment depends on the patient’s age and activity level and the presence of additional injuries
  • Obtain orthopedic consultation when appropriate
  • Initial nonpharmacologic treatment includes rest, ice, compression, and elevation (RICE)
  • For the first 1-3 days, use therapeutic measures that minimize incipient damage and reduce pain and inflammation
  • Consider splinting the injured knee to provide support and to prevent further injury
  • Serviceable devices include immobilizers and handcrafted compressive dressings
  • Detrimental effects of immobilization include joint stiffness, degenerative changes in articular cartilage, muscle atrophy and weakness, and decreased vascularity

Therapy for specific injuries include the following:

  • For first-degree sprains, provide symptomatic treatment (essentially RICE); normal function usually returns quickly
  • Second-degree sprains must be protected by using a cast, cast brace, or a restrictive movement brace; arrange for timely follow-up care
  • Treatment of third-degree sprains depends on the severity and type of instability; some third-degree sprains of ligaments call for surgical repair
  • Treatment for anterior cruciate ligament (ACL) injuries is individualized, influenced by the presence or absence of comorbid pathology, age of the patient, baseline activity level, degree of instability, and associated ligamentous injuries miring the knee
  • Presence of a meniscal tear does not automatically lead to surgical intervention; if the knee is not locked or unstable, conventional treatment (ie, RICE) ordinarily suffices

Reduction of knee dislocation includes the following:

  • Most knee dislocations reduce spontaneously before arrival in the ED; however, when findings suggest neurovascular compromise, attempt to restore circulation with traction or reduction and emergency orthopedic consultation
  • Classify dislocations with respect to the relationship of the tibia on the femur
  • Anterior dislocations occur most commonly
  • Ideally, perform reductions in the operating room with general anesthesia; however, if circumstances preclude this scenario, an attempt in the ED is warranted
  • Barring contraindications, administer conscious sedation
  • With an assistant providing stabilization and countertraction of the thigh, a second person applies longitudinal traction to the leg; this usually suffices for reduction.
  • Reduction of an anterior dislocation may be aided by transposing the femur anteriorly
  • Avoid affixing pressure over the popliteal space; this may exacerbate arterial damage
  • For posterior dislocations, attempt to reinstate the tibia anteriorly
  • After relocation, confirm neurovascular status and immobilize the knee in 15° of flexion
  • Order postreduction images and consultation with the orthopedic surgeon, and obtain an emergency arteriogram

Reduction of patellar dislocation includes the following:

  • Patellar dislocations typically occur in predisposed individuals and tend to recur
  • Patellar dislocations are identified with respect to the patella’s position on the knee joint, with lateral dislocations being most common
  • If the joint has not reduced spontaneously, verify the dislocation radiographically
  • After administering necessary analgesia, place the hip in a mild amount of flexion, and gently press anteriorly and medially on the patella while extending the knee joint
  • Postreduction films should include a sunrise view
  • Other types of patellar dislocations tend to be resistant to closed reduction
  • Aspiration of a Baker cyst may render temporizing relief

See Treatment and Medication for more detail.

Next

Background

Soft tissue injuries of the knee are some of the most common and clinically challenging musculoskeletal disorders in patients presenting to the ED. Annually, more than 1 million emergency department (ED) visits and 1.9 million primary care outpatient visits are for acute knee pain. Therefore, establishing clear-cut diagnostic and therapeutic objectives for these injuries is important.

Knee pain and related symptoms may derive from damage to one or more of the soft tissue structures that stabilize and cushion the knee joint (including the ligaments, muscles, tendons, and menisci), from infection to the knee joint or surrounding structures, or from trauma to the bones forming the joint. In addition to the etiology of the patient's presenting symptom, determine the acuity of the pathologic process as an acute traumatic or infectious event or exacerbation of a chronic overuse or degenerative syndrome.

Accurate and timely diagnosis increases the likelihood of fully restoring normal and pain-free use of the affected knee. For most patients, the severity of the etiology and the injury or pathologic process, acute or chronic, can be determined from a targeted history, focused physical examination, and thoughtful workup including diagnostic imaging (eg, plain radiography).

Pediatric cases

In any child with a traumatic injury, be alert to the possibility of child abuse.

Children with hip disorders, especially a slipped capital femoral epiphysis and Legg-Calvé-Perthes disease, may have referred pain to the knee. Ligamentous damage, meniscal damage, and dislocations (with the exception of patellar dislocations) are rare in children.

Children with open epiphyseal plates may have injuries that can be mistaken for soft-tissue injuries.

The missing of growth-plate injuries in children may result in deformity and growth irregularities. If the patient has circumferential tenderness about the lower part of the femur or the proximal tibia, treat it as a Salter-Harris growth-plate injury, even if radiography findings are normal.

Impetuous stress testing of the knee joint may induce additional damage, displacing a fracture or worsening a growth-plate disturbance.

A completely displaced epiphyseal fracture of the distal femur is the pediatric equivalent of adult knee dislocation. This injury may also harm the popliteal artery.

Osteochondritis dissecans, an intra-articular disorder of unclear etiology, is most common in boys during late childhood or in male adolescents. The condition is characterized by degeneration and recalcification of the articular cartilage and underlying bone. Patients tend to report vague, poorly localized knee pain, as well as morning stiffness or recurrent effusions. Osteochondritic lesions can be radiographically occult, and CT, bone scanning, or MRI may be required to make the diagnosis.

Although not strictly a disease, Osgood-Schlatter disease probably originates from microtrauma, leading to apophysitis at the insertion of the patellar tendon into the tibial tubercle.

Complaints of knee pain generally start in energetic children aged 9-15 years, a time of rapid growth.

Discomfort tends to be localized, and palpation reveals swelling and tenderness over the tibial tubercle.

Boys are affected more commonly than girls; activity exacerbates pain, and bilateral involvement occurs in about 30% of patients.

Initial treatment is conservative, with activity limited to the patient's tolerance.

Geriatric cases

Rupture of the extensor mechanism may precede trivial trauma in the elderly, especially in individuals with coexisting disorders, such as renal failure, systemic lupus erythematosus, hyperparathyroidism, or diabetes mellitus.

Because of underlying degenerative disease, meniscal tears may emerge in older patients with a history of minimal or no trauma. For example, simply rising from a squatting position may cause a tear.

Discomfort and distention related to the knee after a fall may arise from a fracture of the tibial plateau, especially the lateral plateau.

Osteoporosis, commonly in elderly persons, makes bones more vulnerable to fracture. Visualization of fractures on plain images is difficult, and fractures may be overlooked easily. Misdiagnosing this fracture as a soft-tissue injury may lead to additional morbidity, as fracture fragments may be displaced.

Pregnancy

Knee problems, especially underlying meniscal and patellar problems, may worsen with pregnancy because of changes in the biomechanics of weight bearing and shifting in the center of gravity with fetal development.

Production of relaxin hormone during pregnancy may modify ligaments of the knee, in addition to those of the pelvis, increasing knee laxity.

Radiography in pregnancy is always a concern. Although some risk is associated with obtaining diagnostic radiographs in pregnancy, animal and human data do not reveal an increased risk to the fetus when fetal exposure is limited. After 20 weeks' gestation, the risk of radiation exposure that might cause fetal abnormalities is remote; however, avoid unessential radiography. If radiographs are deemed indispensable, shield the patient's abdomen.

Pathophysiology

To understand the various injury patterns associated with trauma to the knee, understanding the anatomy is important. The anatomy of the knee is shown in the image below.

Anatomy of the knee. Anatomy of the knee.

Knee symptoms arise from an alteration or disruption of the normal anatomic structures that impede normal knee function. In mechanical terms, the knee performs like a rolling cam rather than as a simple hinged (ginglymus) joint. As the knee proceeds from flexion to extension, a complex screw-type of motion takes place, with the femoral condyles locking into the tibial plateau as the femur rotates internally. Full knee extension increases the tautness of the major bracing ligaments, transforming the knee into a mechanically rigid structure. Flexion loosens the knee joint by unlocking and disengaging the bracing structures, including retraction of the menisci, thereby enhancing ligamentous laxity and increasing the range of motion (ROM) of the joint.

Two separate but interdependent joints forming the knee are the tibiofemoral articulation and the patellofemoral coupling. Weight-bearing forces, as much as 5 times an individual's body weight, are transmitted through the opposing condyles of the femur and the tibia. Two shock-absorbing cartilaginous menisci interpose between the femur and the tibia, forming the largest synovial joint in the body. The medial meniscus is smaller and more fixed than the lateral meniscus; these features predispose it to injury. A fibrous capsule lined by a synovial membrane also surrounds and bolsters the knee joint but does not contribute to the inherent stability of the joint.

Fitness of the knee joint largely depends on the fortifying ligaments and muscles binding together the femur, tibia, and patella. Two sets of knee ligaments are frequently affected. The first set, lying outside of the knee joint proper, are the extracapsular collateral ligaments. These ligaments consist of the medial collateral ligament (MCL), which opposes extreme abductive and/or valgus forces, and its counterpart, the lateral collateral ligament (LCL), which limits excessive adductive and/or varus pressures. The second set, crisscrossing in the knee joint, are the anterior cruciate ligament (ACL) and the posterior cruciate ligament (PCL), which individually brace against excessive translation in the anteroposterior (AP) plane. The ACL serves as the primary knee stabilizer, preventing forward displacement of the tibia on the femur.

Primarily formed by the quadriceps muscles, the extensor apparatus envelops and stabilizes the patella. At its distal aspect, the quadriceps muscle consolidates into the patellar ligament, ultimately inserting onto the tibial tubercle. Several bursae envelop the knee, including the prepatellar, superficial and deep infrapatellar, and pes anserine bursae, which permit friction-free movement between the various structures. Acute trauma or repetitive occupational stress may incite inflammation; infection and metabolic disorders (eg, gout) are less common etiologies. Inflammation of the bursa then leads to localized tenderness, erythema, and increased warmth. Extensive bursae in this area alleviate potentially damaging frictional forces between the susceptible structures. Fixed in the back of the knee joint, in the popliteal fossa, are vital neurovascular structures, including the popliteal artery.

Definitions and grades of sprains and strains

Sprains to the knee are characterized by the stretching or tearing of noncontractile structures, such as the investing ligaments or of the joint capsule itself, whereas a strain refers to stretching or severing along the course of muscles or tendons. Both collateral ligament and cruciate ligament sprains, as well as muscular strains, are relatively common. Ligamentous (sprain) and muscular (strain) injuries may be classified according to the degree of impairment.

  • Grade I sprain - Stretching but no tearing of the ligament, local tenderness, minimal edema, no gross instability with stress testing, firm end point
  • Grade II sprain - Partial tears of the ligaments, moderate local tenderness, mild instability with stress testing (but firm end point), moderately incapacitating
  • Grade III sprain - Complete tear, discomfort with manipulation but less than expected for degree of injury, variable amount of edema (ranging from negligible to grossly conspicuous), clear instability with stress testing (expressing a mushy end point), severe disability

Specific injuries

See the list below:

  • ACL injury: Rupture of the ACL is among the most serious of the common knee injuries and results from a variety of mechanisms. Most patients with ACL damage complain of immediate and profound pain, exacerbated with motion, and inability to ambulate. Disruption of the ACL may occur alone or with other knee injuries, especially a meniscal injury or tear of the MCL.
  • PCL injury: Patients typically report falling on a flexed knee or sustaining a direct blow to the anterior aspect of the knee (eg, when the knee strikes the dashboard in a motor vehicle accident). PCL harm signifies a major injury and rarely occurs as an isolated injury.

Frequency

United States

Knee pain is a complaint in as many as 20% of the general adult population, accounting for almost 3 million outpatient and emergency department visits per year. Trauma to the knee is the second most common occupational accident. The MCL is the most frequently injured ligament in the knee. ACL damage causes the highest incidence of pathologic joint instability.

In National Collegiate Athletic Association (NCAA) football, one major knee injury occurs per team every year. Sports-related activity accounts for approximately 60% of knee injuries producing ligamentous laxity.

In a study of patients with sport-related knee strain and sprain presenting to US emergency departments from 2002 to 2011, the highest injury rates occurred in football and basketball for males and in soccer and basketball for females; the population most at risk was individuals of both sexes aged15 to 19 years.[1]

International

As in the United States, the incidence of knee injuries is increased in countries where sporting activities, such as skiing, soccer, and basketball, are popular.

Mortality/Morbidity

Patients receiving inappropriate or ill-timed care of knee dislocations may have undue morbidity (eg, amputation) due to vascular complications in the distal leg. Oversight of the magnitude of soft tissue injuries of the knee may result in a failure to expeditiously consider compartment syndrome and its resultant complications, including loss of a limb. Misdiagnosis or mismanagement of damage to supporting structures of the knee may lead to chronic knee instability with subsequent development of degenerative joint disease and/or loss of knee function, including but not limited to an inability to bear weight or ambulate.

Sex

Disorders of the patella and lateral meniscus are generally more common in girls and women than in boys and men. Recent studies also suggest that females are more prone to ACL injuries, which is believed to be due to the fact that the female ACL is both structurally weaker and has a relatively smaller cross sectional diameter. Chondromalacia patellae or patellar malalignment syndrome (ie, premature erosion and degeneration of patellar cartilage) predominates in young women.

Larsen-Johansson disease of the patella, also known as inferior pole patellar chondropathy, is 9 times more prevalent in boys and men than in girls and women, especially in boys aged 10-14 years.

Age

Ligamentous and meniscal injuries are most likely in young to middle-aged adults, whereas children and adolescents are most susceptible to osseous damage. Most patients with a meniscal tear are aged 20-30 years, but a second peak occurs in patients older than 60 years. Meniscal injuries are rare in children younger than 10 years with morphologically normal menisci.

In general, knee dislocations arise from high-energy trauma, such as motor vehicle accidents.[2] The epidemiology of injury follows that of car accidents; therefore, patients tend to be young men.

Overall, 18.1% of US men and 23.5% of US women aged 60 years and older reported knee pain on most days for 6 weeks prior to their medical examination. Additionally, elderly patients may sustain fractures after minimal trauma that typically produces only soft tissue injuries in younger patients.

The region of the extensor mechanism susceptible to disruption is correlated with the patient's age. The older the patient, the more proximal the area of rupture. Disruption of the quadriceps tendon most often occurs in elderly patients, whereas more distal severance of the patellar tendon and avulsion of the tibial tubercle occurs in younger patients.

Clinical Presentation    

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