PPIs, which are commonly used to treat and reduce the production of gastric acids within the stomach have recently been discovered to slow calcium absorption leading to early onset osteoporosis among long-term patients.

Individuals suffering from any of the several conditions associated with gastric acid and who are taking Proton Pump Inhibitors (PPIs) may find themselves at more of a risk for osteoporosis and bone fracture than gastric acid production.

Individuals who are most at risk for the development of osteoporosis and bone fracture are those who have taken PPIs for longer than five years, according to an August 2008 article published in the Canadian Medical Association Journal.

The study echoed results of a similar study published in a December 2006 issue of the Journal of the American Medical Association, which found that long-term, high-dose consumption of PPIs contributed to hip fractures among patients.

Nearly 44 million Americans suffer from osteoporosis, which is nearly 55 percent of the 50 plus age group, according to the National Osteoporosis Foundation as quoted in a September 2008 American Medical News article.

What are PPIs Used For?

Proton Pump Inhibitors (PPIs) were introduced to help patients suffering from an array of conditions find relief with a reduction of gastric acid production. PPIs can be used for treatment of the following:

* Zollinger-Ellison syndrome

* Gastroesophageal Reflux Disease (GERD)

* Stress gastritis

* Barrett's esophagus

* Peptic ulcer disease (PUD)

* Dyspepsia

* Laryngopharyngeal Reflux Disease

* Gastrinomas

Conditions causing hypersecretion of acid

The PPIs account for a nearly $13 billion dollar a year industry, considered one of the most popular drugs available coming in only second to cholesterol drugs, according to an article from The Wall Street Journal.

Proton Pump Inhibitor Side Effects

While two medical studies have reported significant dangers associated with consuming PPIs, their have been no proton pump inhibitor recalls and Sameer Dev Saini, MD, the lead author of the Journal of American Medical Associations believes that the evidence is not concrete enough for patients to receive different prescription habits, according to the American Medical News article.

Medical professionals are, however, advising that patients taking PPIs also increase their intake of calcium and vitamin D. Some of the most reoccurring PPI symptoms are:

* Mild dizziness

* Headache

* Nausea

* Diarrhea

* Constipation

* Rash

Patients who are currently taking PPIs and are suffering from the following side effects may want to consider consulting a physician to ensure the PPI is not causing unseen damages:

* brittle bones

* bone fractures

* breaking bones

* osteoporosis

Overcoming PPI Risks

PPIs are most commonly known for treating or reducing heartburn, however, there are several other treatments that can be considered to reduce heartburn as well as consumption of PPIs, which have severe risks associated with them. Also, the following should be considered as alternative treatments including:

* Change in diet, including cutting back on high-fat meals, alcohol, caffeine and soda

* Consuming antacids, such as Tums, Rolaids, Mylanta, to neutralize acid production

* Consumption of H-2 Blockers (Pepcid, Zantac and Tagament), which block acid production

* Pro-motility drugs, such as Propulsid, that hasten gastric emptying

* Antireflux surgery

Several of the more common PPIs brand names include:

* Aciphex (rabeprazole)

* Prilosec (omepraazole)

* Nexium (esomeprazole)

* Prevacid (lansoprazole)

* Protonix (pantoprazole)

Individuals suffering from any of the above conditions who have been taking PPIs for several years should consult a medical professional immediately, as the patient may be at extreme risks for developing early onset osteoporosis.

Consulting with a legal professional may offer the deserved security necessary as well as monetary compensation for the PPI side effects.

Article Tags: Suffering From, Gastric Acid, American Medical, Acid Production, Taking Ppis